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Efficacy of Radiotherapy for Painful Bone Metastases During the Last 12 Weeks of Life: Results from the Dutch Bone Metastasis Study
Single-Fraction Palliative Radiotherapy for Bone Metastases
JJ Meeuse, YM van der Linden, G van Tienhoven, ROB Gans, JWH Leer, AKL Reyners, for the Dutch Bone Metastasis Study Group
20100211
2010 Mar 11
Cancer
Efficacy of Radiotherapy for Painful Bone Metastases During the Last 12 Weeks of Life: Results from the Dutch Bone Metastasis Study
Cancer. 2010 Mar 11;116(11):2716-2725, JJ Meeuse, YM van der Linden, G van Tienhoven, ROB Gans, JWH Leer, AKL Reyners, for the Dutch Bone Metastasis Study Group
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Abstract
SUMMARY
OncologySTAT Editorial Team
Pain due to bone metastases in patients with advanced cancer is amenable to palliative radiotherapy, especially single-fraction radiotherapy, as evidenced by a large number of controlled studies. However, pain relief requires 3 to 4 weeks’ treatment, and the benefit of this form of palliative intervention in patients with a short life expectancy is not clear. The Dutch Bone Metastasis Study, reported by Meeuse et al., investigated the effect of radiotherapy in such patients. The study randomized...