Journal Scans
Efficacy of Dexmethylphenidate for the Treatment of Fatigue After Cancer Chemotherapy: A Randomized Clinical Trial
Dexmethylphenidate Relieves Chemotherapy-Related Fatigue
EE Lower, S Fleishman, A Cooper, J Zeldis, H Faleck, Z Yu, D Manning
20091001
2009 Nov 1
J Pain Symptom Manage
Efficacy of Dexmethylphenidate for the Treatment of Fatigue After Cancer Chemotherapy: A Randomized Clinical Trial
J Pain Symptom Manage. 2009 Nov 1;38(5):650-662, EE Lower, S Fleishman, A Cooper, J Zeldis, H Faleck, Z Yu, D Manning
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Abstract
Abstract
Cancer and its treatment can induce subjective and objective evidence of diminished functional capacity encompassing physical fatigue and cognitive impairment. Dexmethylphenidate (D-MPH; the D-isomer of methylphenidate) was evaluated for treatment of chemotherapy-related fatigue and cognitive impairment. A randomized, double-blind, placebo-controlled, parallel-group study evaluated the potential therapeutic effect and safety of D-MPH in the treatment of patients with chemotherapy-related fatigue....