Journal Scans
Effects of Tamoxifen and Raloxifene on Memory and Other Cognitive Abilities: Cognition in the Study of Tamoxifen and Raloxifene
Tamoxifen Is Comparable to Raloxifene in Effects on Cognition
C Legault, PM Maki, SM Resnick, L Coker, P Hogan, TB Bevers, SA Shumaker
20090821
2009 Sept 21
J Clin Oncol
Effects of Tamoxifen and Raloxifene on Memory and Other Cognitive Abilities: Cognition in the Study of Tamoxifen and Raloxifene
J Clin Oncol. 2009 Sept 21; Epub ahead of print, C Legault, PM Maki, SM Resnick, L Coker, P Hogan, TB Bevers, SA Shumaker
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Abstract
SUMMARY
OncologySTAT Editorial Team
Demonstration that tamoxifen and raloxifene are similarly effective in reducing the risk of invasive breast cancer shifts the focus in choosing between the 2 drugs to differences in their adverse effects. One area of concern is the potential for cognitive impairment from treatment with these drugs. The effect of tamoxifen on cognitive function has not been well studied, however, and the effect of raloxifene on cognitive function is unclear. Some small studies with raloxifene have reported little...
