Journal Scans
Effective Reduction of Gastric Cancer Risk With Regular Use of Nonsteroidal Anti-Inflammatory Drugs in Helicobacter Pylori–Infected Patients
NSAIDs Protect Against Gastric Cancer in Patients With Gastric Ulcers
CY Wu, MS Wu, KN Kuo, CB Wang, YJ Chen, JT Lin
20100417
2010 May 17
J Clin Oncol
Effective Reduction of Gastric Cancer Risk With Regular Use of Nonsteroidal Anti-Inflammatory Drugs in Helicobacter Pylori–Infected Patients
J Clin Oncol. 2010 May 17;[Epub Ahead of Print], CY Wu, MS Wu, KN Kuo, CB Wang, YJ Chen, JT Lin
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Abstract
SUMMARY
OncologySTAT Editorial Team
Chronic inflammation, such as that associated with Helicobacter pylori (H pylori) infection, plays a role in gastric carcinogenesis. Meta-analyses have shown that use of aspirin and nonsteroidal anti-inflammatory drugs (NSAIDs) is associated with a reduced risk of gastric cancer. Wu et al conducted a retrospective cohort study to determine the interaction between NSAID use and H pylori infection. In particular, the objective of the analysis was to determine the subpopulation for whom the benefits...
