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EORTC Melanoma Group Sentinel Node Protocol Identifies High Rate of Submicrometastases According to Rotterdam Criteria
EORTC Sentinel Node Protocol Shows High Positivity Rate in Melanoma
APT van der Ploeg, ACJ van Akkooi, PIM Schmitz, S Koljenovic, C Verhoef, AMM Eggermont
20100612
2010 Jul 12
Eur J Cancer
EORTC Melanoma Group Sentinel Node Protocol Identifies High Rate of Submicrometastases According to Rotterdam Criteria
Eur J Cancer. 2010 Jul 12;[Epub Ahead of Print], APT van der Ploeg, ACJ van Akkooi, PIM Schmitz, S Koljenovic, C Verhoef, AMM Eggermont
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Abstract
Abstract
Sentinel node (SN) status is the most important prognostic factor for disease-free survival (DFS) and overall survival (OS) in stages I–II melanoma. We evaluated the positive sentinel node identification rate of the EORTC Melanoma Group (MG) protocol as well as its capacity to identify minimal tumour burden, according to the Rotterdam Criteria in 421 consecutive patients. Correlations between primary tumour characteristics and SN tumour burden were investigated. The same 2 pathologists worked up...
