Journal Scans
Dynamic Model for Predicting Death Within 12 Months in Patients With Primary or Post–Polycythemia Vera/Essential Thrombocythemia Myelofibrosis
Dynamic Prognostic Model Predicts Highest-Risk Disease in Myelofibrosis
C Tam, H Kantarjian, J Cortes, A Lynn, S Pierce, L Zhou, M Keating, D Thomas, S Verstovsek
20090828
2009 Sept 28
J Clin Oncol
Dynamic Model for Predicting Death Within 12 Months in Patients With Primary or Post–Polycythemia Vera/Essential Thrombocythemia Myelofibrosis
J Clin Oncol. 2009 Sept 28; Epub ahead of print, C Tam, H Kantarjian, J Cortes, A Lynn, S Pierce, L Zhou, M Keating, D Thomas, S Verstovsek
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Abstract
SUMMARY
OncologySTAT Editorial Team
The myeloproliferative disorder myelofibrosis follows a highly variable course in different patients. The median survival is approximately 5 years, but some patients die within 1 year and others survive for longer than 10 years. This large variability in prognosis makes it very difficult to advise patients about therapy, especially the timing of allogeneic stem-cell transplantation, which carries a very high treatment-related mortality. A model to help physicians identify patients in the highest...
