Detection of Extra-Axillary Lymph Node Involvement With FDG PET/CT in Patients With Stage II–III Breast Cancer

Eur J Cancer. 2010 Aug 18;[Epub Ahead of Print], TS Aukema, ME Straver, M-J TFD Vrancken Peeters, NS Russell, KGA Gilhuijs, WV Vogel, EJT Rutgers, RA Valdés Olmos

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Abstract

Abstract

Purpose: The aim of this prospective study was to assess the incidence of extra-axillary lymph node involvement on baseline FDG PET/CT in patients with stage II–III breast cancer scheduled for neo-adjuvant chemotherapy. Methods: Patients with invasive breast cancer of >3 cm and/or proven axillary lymph node metastasis were included for before neo-adjuvant chemotherapy. Baseline ultrasound of the infra- and supraclavicular regions was performed with fine-needle biopsy as needed. Subsequently FDG PET/CT...

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