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Decision Model of Segmental Compared With Total Abdominal Colectomy for Colon Cancer in Hereditary Nonpolyposis Colorectal Cancer
SEG and TAC Equivalent in Hereditary Colon Cancer
T Maeda, RR Cannom, RW Beart Jr, DA Etzioni
20100101
2010 Feb 1
J Clin Oncol
Decision Model of Segmental Compared With Total Abdominal Colectomy for Colon Cancer in Hereditary Nonpolyposis Colorectal Cancer
J Clin Oncol. 2010 Feb 1; Epub ahead of print, T Maeda, RR Cannom, RW Beart Jr, DA Etzioni
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Abstract
SUMMARY
OncologySTAT Editorial Team
The small proportion of patients with colorectal cancer who also have Lynch syndrome, ie, hereditary nonpolyposis colorectal cancer (HNPCC), are younger and more likely to have multiple synchronous or metachronous colorectal cancers than are patients who do not have HNPCC. Total abdominal colectomy with ileo-rectal anastomosis (TAC) has been suggested as a standard therapy for HNPCC patients with a primary colorectal cancer, to decrease the risk of metachronous cancer. Compared with segmental colectomy...