Journal Scans
Clinical Response of Large Cell Neuroendocrine Carcinoma of the Lung to Perioperative Adjuvant Chemotherapy
Adjuvant Chemotherapy for Large-Cell Neuroendocrine Carcinoma of the Lung
H Saji, M Tsuboi, J Matsubayashi, K Miyajima, Y Shimada, K Imai, Y Kato, J Usuda, N Kajiwara, O Uchida, T Ohira, T Hirano, K Mukai, H Kato, N Ikeda
20100001
2010 Jan 1
Anti-Cancer Drugs
Clinical Response of Large Cell Neuroendocrine Carcinoma of the Lung to Perioperative Adjuvant Chemotherapy
Anti-Cancer Drugs. 2010 Jan 1;21(1):89-93, H Saji, M Tsuboi, J Matsubayashi, K Miyajima, Y Shimada, K Imai, Y Kato, J Usuda, N Kajiwara, O Uchida, T Ohira, T Hirano, K Mukai, H Kato, N Ikeda
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Abstract
Abstract
Patients with large cell neuroendocrine carcinoma (LCNEC) of the lung are considered to have poor prognosis. However, the benefit of adjuvant chemotherapy for these patients has not been established. In this study, we retrospectively evaluated the efficacy of perioperative chemotherapy for patients with completely resected LCNEC in a single-center setting. From 1999 through 2007, 45 patients with surgically resected LCNEC or mixed LCNEC containing at least one portion of the neuroendocrine differentiation...
