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Clinical Outcome of Dose-Escalated Image-Guided Radiotherapy for Spinal Metastases
Dose-Escalated Image-Guided Radiotherapy for Spinal Metastases
M Guckenberger, J Goebel, J Wilbert, K Baier, A Richter, RA Sweeney, K Bratengeier, M Flentje
20091001
2009 Nov 1
Int J Radiat Oncol Biol Phys
Clinical Outcome of Dose-Escalated Image-Guided Radiotherapy for Spinal Metastases
Int J Radiat Oncol Biol Phys. 2009 Nov 1;75(3):828-835, M Guckenberger, J Goebel, J Wilbert, K Baier, A Richter, RA Sweeney, K Bratengeier, M Flentje
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Abstract
Abstract
Purpose: To evaluate the outcomes after dose-escalated radiotherapy (RT) for spinal metastases and paraspinal tumors. Methods and Materials: A total of 14 patients, 12 with spinal metastases and a long life expectancy and 2 with paraspinal tumors, were treated for 16 lesions with intensity-modulated, image-guided RT. A median biologic effective dose of 74 Gy10 (range, 55–86) in a median of 20 fractions (range, 3–34) was prescribed to the target volume. The spinal canal was treated to 40 Gy in 20...
