Circulating Tumour Cells Early Predict Progression-Free and Overall Survival in Advanced Colorectal Cancer Patients Treated With Chemotherapy and Targeted Agents

Ann Oncol. 2010 May 1;21(5):1006-1012, J Tol, M Koopman, MC Miller, A Tibbe, A Cats, GJ Creemers, AH Vos, ID Nagtegaal, LW Terstappen, CJ Punt

TAKE-HOME MESSAGE

EXPERT COMMENTARY

Abstract

SUMMARY

OncologySTAT Editorial Team

In the treatment of advanced colorectal cancer (ACC), there is a growing need for early predictive markers of response to therapy, including therapy using targeted agents, to avoid unnecessary treatment in patients unlikely to respond. KRAS mutation status is one marker used to predict response to inhibitors of epidermal growth factor receptor, but markers with broader applicability would be useful. Tol et al evaluated the prognostic and predictive role of prediagnostic levels of circulating tumor...

NOT A MEMBER?

Registration is FREE

  • Up-to-date oncology news
  • Journal article summaries
  • Commentaries and interviews
  • Drug and interactions database
  • Chemotherapy regimens
  • Daily e-newsletters

 

About Our Journal Scans

View a list of journals that the OncologySTAT editorial team scans every week in order to bring you the most practice-relevant original research and review articles.

Sign up for our newsletters

Too busy to follow cancer's top stories? Sign-up for 1 or more of our free newsletters -- delivered weekly to your inbox.

Cancer Type

  • Bladder
  • Bone
  • Breast
  • Breast (ER-Positive)
  • CNS/Brain
  • Colon and Rectum
  • Endocrine System
  • Esophagus
  • GYN (Non-Ovary)
  • GYN (Ovary)
  • Head and Neck
  • Hodgkin's Lymphoma
  • Kidney (Renal Cell)
  • Leukemia
  • Liver and Bile Duct
  • Lung
  • Multiple Myeloma
  • Myelodysplastic Syndrome
  • Myeloproliferative Diseases
  • Non-Hodgkin's Lymphoma
  • Pancreas
  • Pediatric Cancers
  • Prostate
  • Rare Cancers
  • Skin
  • Soft-Tissue Sarcoma
  • Stomach
  • Testicle
  • Forgot your password?
    Not a member? Free registration