Journal Scans
Circulating Tumor Cells: A Useful Predictor of Treatment Efficacy in Metastatic Breast Cancer
Circulating Tumor Cell Counts Predict Breast Cancer Treatment Outcomes
MC Liu, PG Shields, RD Warren, P Cohen, M Wilkinson, YL Ottaviano, SB Rao, J Eng-Wong, F Seillier-Moiseiwitsch, A-M Noone, C Isaacs
20090814
2009 Sept 14
J Clin Oncol
Circulating Tumor Cells: A Useful Predictor of Treatment Efficacy in Metastatic Breast Cancer
J Clin Oncol. 2009 Sept 14; Epub ahead of print, MC Liu, PG Shields, RD Warren, P Cohen, M Wilkinson, YL Ottaviano, SB Rao, J Eng-Wong, F Seillier-Moiseiwitsch, A-M Noone, C Isaacs
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Abstract
SUMMARY
OncologySTAT Editorial Team
Circulating tumor cells (CTCs) are found in the peripheral blood of patients with breast cancer and other forms of cancer. The number of CTCs can be measured using immunomagnetic platforms. A previous study using one such methodology determined that the detection of ≥5 CTCs per 7.5 mL of blood was associated with reduced progression-free survival (PFS) and overall survival (OS); conversely, a lower number of CTCs (<5) was associated with treatment response and improved PFS and OS The present study...
