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Chromogranin-A and N-Terminal Pro-Brain Natriuretic Peptide: An Excellent Pair of Biomarkers for Diagnostics in Patients With Neuroendocrine Tumor
NT-proBNP and CgA Levels Are Prognostic in Neuroendocrine Tumors
CM Korse, BG Taal, CA de Groot, RH Bakker, JMG Bonfrer
20090710
2009 Aug 10
J Clin Oncol
Chromogranin-A and N-Terminal Pro-Brain Natriuretic Peptide: An Excellent Pair of Biomarkers for Diagnostics in Patients With Neuroendocrine Tumor
J Clin Oncol. 2009 Aug 10; Epub ahead of print, CM Korse, BG Taal, CA de Groot, RH Bakker, JMG Bonfrer
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Abstract
SUMMARY
OncologySTAT Editorial Team
Carcinoid syndrome occurs in 20% to 30% of patients diagnosed with neuroendocrine tumor (NET). The syndrome is caused by overproduction of vasoactive mediators and presents with abdominal pain, diarrhea, and flushing. Ensuing carcinoid heart disease (CHD), which is associated with overproduction of serotonin, is a major cause of death in patients with NET, including 20% to 70% of those with liver metastasis. Echocardiography is often used in the follow-up of patients with NET. This procedure is...
