Chemotherapy of Advanced Small-Bowel Adenocarcinoma: A Multicenter AGEO Study

Ann Oncol. 2010 Sept 1;21(9):1786-1793, A Zaanan, L Costes, M Gauthier, D Malka, C Locher, E Mitry, D Tougeron, T Lecomte, J-M Gornet, I Sobhani, V Moulin, P Afchain, J Taïeb, F Bonnetain, T Aparicio

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Abstract

SUMMARY

OncologySTAT Editorial Team

Small-bowel adenocarcinoma (SBA) is a very rare disease, typically diagnosed at an advanced stage and carrying a poor prognosis. Clinical studies are lacking in SBA, and thus no standard first-line treatment has been established. Results of a recent retrospective analysis of 80 patients suggested that improved responses could be obtained with 5-fluorouracil (5-FU) plus a platinum derivative in comparison with other chemotherapy regimens. In this retrospective study, Zaanan et al evaluated the efficacy...

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