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Chemoradiation in Locally Advanced Cervical Carcinoma: An Analysis of Cisplatin Dosing and Other Clinical Prognostic Factors
Chemoradiation in Locally Advanced Cervical Carcinoma
EK Nugent, AS Case, JT Hoff, I Zighelboim, LL DeWitt, K Trinkhaus, DG Mutch, PH Thaker, LS Massad, JS Rader
20100201
2010 Mar 1
Gynecol Oncol
Chemoradiation in Locally Advanced Cervical Carcinoma: An Analysis of Cisplatin Dosing and Other Clinical Prognostic Factors
Gynecol Oncol. 2010 Mar 1;116(3):438-441, EK Nugent, AS Case, JT Hoff, I Zighelboim, LL DeWitt, K Trinkhaus, DG Mutch, PH Thaker, LS Massad, JS Rader
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Abstract
Abstract
Objectives: The aim of this study was to evaluate the effect of number of chemotherapy cycles and other clinical and pathologic factors on progression-free (PFS) and overall survival (OS) in patients with newly diagnosed cervical cancer. Methods: We identified 118 patients with locally advanced cervical cancer (stages IB2–IVA) treated with combination weekly cisplatin (40 mg/m2) and radiation therapy (RT) between 2003 and 2007. Kaplan–Meier and Cox proportional hazard models were utilized to evaluate...
