Cardiac Function in 5-Year Survivors of Childhood Cancer: A Long-Term Follow-up Study

Arch Intern Med. 2010 Jul 26;170(14):1256-1261, HJ van der Pal, EC van Dalen, M Hauptmann, WE Kok, HN Caron, C van den Bos, F Oldenburger, CC Koning, FE van Leeuwen, LC Kremer

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Abstract

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OncologySTAT Editorial Team

The greatly elevated risk of cardiovascular disease (CVD) among childhood cancer survivors long after the initial cancer diagnosis and treatment has been linked to various factors, such as anthracycline treatment, radiation dose, age at diagnosis, and female sex. In order to determine the risk of morbidity and mortality attributed to different cardiotoxic therapies, investigators examined the occurrence of left ventricular (LV) dysfunction and associated risk factors in a large cohort of long-term...

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