Can Chemotherapy Be Discontinued in Unresectable Metastatic Colorectal Cancer? The GERCOR OPTIMOX2 Study
Maintenance With Simplified LV5FU2 vs Chemotherapy Discontinuation in Unresectable Metastatic Colorectal Cancer
B Chibaudel, F Maindrault-Goebel, G Lledo, L Mineur, T André, M Bennamoun, M Mabro, P Artru, E Carola, M Flesch, O Dupuis, P Colin, AK Larsen, P Afchain, C Tournigand, C Louvet, A de Gramont
Can Chemotherapy Be Discontinued in Unresectable Metastatic Colorectal Cancer? The GERCOR OPTIMOX2 Study
J Clin Oncol. 2009 Sept 28;[Epub Ahead of Print], B Chibaudel, F Maindrault-Goebel, G Lledo, L Mineur, T André, M Bennamoun, M Mabro, P Artru, E Carola, M Flesch, O Dupuis, P Colin, AK Larsen, P Afchain, C Tournigand, C Louvet, A de Gramont
ABSTRACT
The results of the OPTIMOX2 study showed that maintenance therapy with simplified LV5FU2 between induction therapy with and reintroduction of mFOLFOX7 reduced the risk of oxaliplatin failure by 29% when...