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Body Composition Changes During Androgen Deprivation Therapy for Prostate Cancer: A 2-Year Prospective Study
Androgen Deprivation Therapy Changes Body Composition
GJ van Londen, ME Levy, S Perera, JB Nelson, SL Greenspan
20081001
2008 Nov 1
Crit Rev Oncol Hematol
Body Composition Changes During Androgen Deprivation Therapy for Prostate Cancer: A 2-Year Prospective Study
Crit Rev Oncol Hematol. 2008 Nov 1;68(2):172-177, GJ van Londen, ME Levy, S Perera, JB Nelson, SL Greenspan
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Abstract
Abstract
Background: Little is known about the long-term impact of androgen deprivation therapy (ADT) on body composition in men with prostate cancer. We compared body composition parameters in men with non-metastatic prostate cancer on or not on therapy with healthy, age-matched controls at baseline and monitored changes over a 2-year period. Methods: We measured body fat mass and lean body mass in 81 men with prostate cancer on no ADT, 43 men on acute ADT(less than 6 months), 67 men on chronic ADT (more...