Journal Scans
Benefit of Consolidative Radiation Therapy in Patients With Diffuse Large B-Cell Lymphoma Treated With R-CHOP Chemotherapy
R-CHOP Plus Radiotherapy in Diffuse Large B-Cell Lymphoma
J Phan, A Mazloom, LJ Medeiros, TG Zreik, C Wogan, F Shihadeh, MA Rodriguez, L Fayad, N Fowler, V Reed, P Horace, BS Dabaja
20100716
2010 Aug 16
J Clin Oncol
Benefit of Consolidative Radiation Therapy in Patients With Diffuse Large B-Cell Lymphoma Treated With R-CHOP Chemotherapy
J Clin Oncol. 2010 Aug 16;[Epub Ahead of Print], J Phan, A Mazloom, LJ Medeiros, TG Zreik, C Wogan, F Shihadeh, MA Rodriguez, L Fayad, N Fowler, V Reed, P Horace, BS Dabaja
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Abstract
SUMMARY
OncologySTAT Editorial Team
Diffuse large B-cell lymphoma (DLBCL) is a heterogeneous lymphoma, usually associated with an aggressive presentation. The established standard of care for DLBCL is rituximab with chemotherapy containing cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP). Although radiation therapy was initially considered the first curative treatment for aggressive non-Hodgkin’s lymphoma, its role in DLBCL has become controversial, with several studies reporting conflicting results. Moreover, none...
