Aromatase Inhibitor–Induced Carpal Tunnel Syndrome: Results From the ATAC Trial

J Clin Oncol. 2009 Sept 14; Epub ahead of print, I Sestak , F Sapunar, J Cuzick

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Abstract

SUMMARY

OncologySTAT Editorial Team

Women are 3 times more likely than men to develop carpal tunnel syndrome (CTS). Because CTS appears to be associated with menopause, hormones may be involved in its etiology in women. Aromatase inhibitors, including anastrozole, exemestane, and letrozole, have been linked to joint symptoms and also to CTS. This study evaluated risk factors related to CTS and the impact of anastrozole treatment on these factors, using data from a follow-up analysis of the Arimidex, Tamoxifen, Alone or in Combination...

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