Journal Scans
Alternating Systemic and Hepatic Artery Infusion Therapy for Resected Liver Metastases From Colorectal Cancer
Alternating Systemic and HAI Chemotherapy in Metastatic CRC
SR Alberts, MS Roh, MR Mahoney, MJ O'Connell, DM Nagorney, L Wagman, TC Smyrk, TL Weiland, LL Lai, RE Schwarz, R Molina, T Dentchev, JS Bolton
20100004
2010 Jan 4
J Clin Oncol
Alternating Systemic and Hepatic Artery Infusion Therapy for Resected Liver Metastases From Colorectal Cancer
J Clin Oncol. 2010 Jan 4; Epub ahead of print, SR Alberts, MS Roh, MR Mahoney, MJ O'Connell, DM Nagorney, L Wagman, TC Smyrk, TL Weiland, LL Lai, RE Schwarz, R Molina, T Dentchev, JS Bolton
TAKE-HOME MESSAGE
Abstract
SUMMARY
OncologySTAT Editorial Team
Surgery can provide a long-term survival benefit in certain patients who have resectable metastases from colorectal cancer (CRC). In addition, the introduction of oxaliplatin-based chemotherapy for metastatic CRC has further improved response rates and overall survival in these patients. Unfortunately, a large percentage of patients will develop recurrence in the liver after metastasectomy. Thus, use of regionally-delivered adjuvant chemotherapy is of interest. Fluorouracil therapy delivered by...
