Journal Scans
Alpha-Fetoprotein Response After Locoregional Therapy for Hepatocellular Carcinoma: Oncologic Marker of Radiologic Response, Progression, and Survival
Prognostic Significance of AFP in Hepatocellular Carcinoma
A Riaz, RK Ryu, LM Kulik, MF Mulcahy, RJ Lewandowski, J Minocha, SM Ibrahim, KT Sato, TT Baker, FH Miller, S Newman, R Omary, M Abecassis, AB Benson III, R Salem
20090905
2009 Oct 5
J Clin Oncol
Alpha-Fetoprotein Response After Locoregional Therapy for Hepatocellular Carcinoma: Oncologic Marker of Radiologic Response, Progression, and Survival
J Clin Oncol. 2009 Oct 5; Epub ahead of print, A Riaz, RK Ryu, LM Kulik, MF Mulcahy, RJ Lewandowski, J Minocha, SM Ibrahim, KT Sato, TT Baker, FH Miller, S Newman, R Omary, M Abecassis, AB Benson III, R Salem
TAKE-HOME MESSAGE
Abstract
SUMMARY
OncologySTAT Editorial Team
Alpha-fetoprotein (AFP) is a widely used marker for hepatocellular carcinoma (HCC). Previous studies have suggested that a change in AFP may be a marker for response to surgery or systemic chemotherapy. This study evaluated whether AFP response could be a prognostic factor for survival in patients undergoing locoregional therapy for HCC. The results showed that AFP response was a reliable predictor of radiologic response, progression, and survival. This study included 125 patients with HCC isolated...
