Agent Orange Exposure, Vietnam War Veterans, and the Risk of Prostate Cancer
Cancer. 2008 Nov 1;113(9):2464-2470, K Chamie, RW deVere White, D Lee, J Ok, LM Ellison
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Abstract
Abstract
BACKGROUND: It has been demonstrated that Agent Orange exposure increases the risk of developing several soft tissue malignancies. Federally funded studies, now nearly a decade old, indicated that there was only a weak association between exposure and the subsequent development of prostate cancer. Because Vietnam War veterans are now entering their 60s, the authors reexamined this association by measuring the relative risk of prostate cancer among a cohort of men who were stratified as either exposed...
SUMMARY
OncologySTAT Editorial Team
From 1962 to 1971, the United States sprayed the phenoxy-herbicide Agent Orange over a large area of South Vietnam. Agent Orange was often contaminated with the highly toxic and oncogenic compound 2,3,7,8-tetrachlorodibenzo-p-dioxin. Although Agent Orange exposure has been linked to soft-tissue sarcomas, Hodgkin’s disease, and non-Hodgkin’s lymphoma, its association with prostate cancer has not been confirmed. Now, decades later, reassessment of prostate cancer risk associated with Agent Orange exposure...
