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Achieving an Undetectable PSA After Radiotherapy for Biochemical Progression After Radical Prostatectomy Is an Independent Predictor of Biochemical Outcome—Results of a Retrospective Study
Predictive Value of Undetectable PSA After Post-Prostatectomy RT
T Wiegel, G Lohm, D Bottke, S Höcht, K Miller, A Siegmann, M Schostak, K Neumann, W Hinkelbein
20090215
2009 Mar 15
Int J Radiat Oncol Biol Phys
Achieving an Undetectable PSA After Radiotherapy for Biochemical Progression After Radical Prostatectomy Is an Independent Predictor of Biochemical Outcome—Results of a Retrospective Study
Int J Radiat Oncol Biol Phys. 2009 Mar 15;73(4):1009-1016, T Wiegel, G Lohm, D Bottke, S Höcht, K Miller, A Siegmann, M Schostak, K Neumann, W Hinkelbein
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Abstract
Abstract
Purpose: Salvage radiotherapy (SRT) is commonly used to treat patients with biochemical failure after radical prostatectomy (RP). Retrospective series have demonstrated biochemical response in approximately 60–75% of patients, but only a significantly lower rate of patients achieves a response with a decrease of the prostate-specific antigen (PSA) to a value below the limits of detectability. Therefore, long-term response at 10 years is only about 20–25% in all of these patients. The purpose of this...