Prevalence and clinical relevance of pathological hepatic changes occurring after neoadjuvant chemotherapy for colorectal liver metastases
Catherine Hubert, Caroline Fervaille, Christine Sempoux, Yves Horsmans, Yves Humblet, Jean-Pascal Machiels, Francis Zech, Antonino Ceratti, Jean-François Gigot
20100101
2010 Feb 1
Surgery
Prevalence and clinical relevance of pathological hepatic changes occurring after neoadjuvant chemotherapy for colorectal liver metastases
Surgery. 2010 Feb;147(2):185-194, Catherine Hubert, Caroline Fervaille, Christine Sempoux, Yves Horsmans, Yves Humblet, Jean-Pascal Machiels, Francis Zech, Antonino Ceratti, Jean-François Gigot
BackgroundHepatotoxicity from neoadjuvant chemotherapy before liver resection for colorectal metastases (CRLM) has been recently reported. The purpose of the present study was to evaluate the prevalence and the clinical relevance of this phenomenon. It was a retrospective study conducted at an academic secondary referral hospital.MethodsOne hundred patients suffering from CRLM and having undergone the resection of at least 1 liver segment (114 hepatectomies; 100 first, 13 second, 1 third) were enrolled....
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