Preemptive Analgesia Reduces Pain After Radical Axillary Lymph Node Dissection

J Surg Res. 2010 Jul;162(1):88-94, Heiko Neuss, Gerold Koplin, Oliver Haase, Christian Reetz, Julian W. Mall

BackgroundAnalyzing prospective data of our melanoma patients, we registered a suboptimal pain score under mobilization after radical axillary lymph node dissection (RALND). We performed a randomized, double blinded clinical trial to investigate the effects of a preemptive Parecoxib analgesic during the perioperative course.Materials and MethodsBetween October 2006 and December 2007, 32 patients with stage III/IV melanoma underwent therapeutic RALND and were randomized into two groups. Patients received...

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