t(8;21)(q22;q22) Translocation involving AML1 and ETO in B lymophoblastic leukemia
Huan-You Wang, Carlos A. Tirado
20100101
2010 Feb 1
Hum Pathol
t(8;21)(q22;q22) Translocation involving AML1 and ETO in B lymophoblastic leukemia
Hum Pathol. 2010 Feb;41(2):286-292, Huan-You Wang, Carlos A. Tirado
t(8;21)(q22;q22) giving rise to RUNX1/RUNX1T1 fusion transcript is a recurrent non-random chromosomal translocation, accounting for approximately 5% of cases of acute myeloid leukemia and 10% of acute myeloid leukemia with maturation. Studies have demonstrated so far that t(8;21)(q22;q22) occurs only in acute myeloid leukemia, and B lymphoblastic leukemia with t(8;21)(q22;q22) has not been reported in the literature. In the present study, we report a 44-year-old woman with a diagnosis of a B lymphoblastic...