What can we learn from the errors in the frozen section diagnosis of pulmonary carcinoid tumors? An evidence-based approach

Hum Pathol. 2009 Jan;40(1):1-9, Ruta Gupta, Aditi Dastane, Robert J. Mckenna, Alberto M. Marchevsky

ABSTRACT

The intraoperative diagnosis of pulmonary neuroendocrine tumors can be difficult. Frozen section diagnosis was requested on 87 neuroendocrine tumors including 58 typical carcinoids, 8 atypical carcinoids, 18 large cell neuroendocrine carcinomas, and 3 small cell carcinomas from 2405 patients that underwent frozen section diagnosis at Cedars-Sinai Medical Center from 2002 to 2007. The deferral and error rate for carcinoid tumors was 4.13% and 7.5%, respectively, and resulted in 4 unnecessary lobectomies...

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