Minimal-change nephrotic syndrome preceding Hodgkin lymphoma by 5 years with expression of tumor necrosis factor α in Hodgkin-Reed-Sternberg cells
Shoko Nakayama, Taiji Yokote, Kichinosuke Kobayashi, Yuji Hirata, Toshikazu Akioka, Nobuya Hiraoka, Satoko Oka, Takuji Miyoshi, Takayuki Takubo, Motomu Tsuji, Toshiaki Hanafusa
20100701
2010 Aug 1
Hum Pathol
Minimal-change nephrotic syndrome preceding Hodgkin lymphoma by 5 years with expression of tumor necrosis factor α in Hodgkin-Reed-Sternberg cells
Hum Pathol. 2010 Aug;41(8):1196-1199, Shoko Nakayama, Taiji Yokote, Kichinosuke Kobayashi, Yuji Hirata, Toshikazu Akioka, Nobuya Hiraoka, Satoko Oka, Takuji Miyoshi, Takayuki Takubo, Motomu Tsuji, Toshiaki Hanafusa
A 76-year-old man developed minimal-change nephrotic syndrome (NS). After treatment with prednisolone failed to induce sustained remission, cyclosporin was added. The NS improved, and prednisolone and cyclosporin doses were gradually decreased. However, he had repeated relapses of the syndrome, and at each relapse, the drug doses were increased. After 5 years, the patient developed left inguinal lymphadenopathy. The histological diagnosis was mixed cellularity classical Hodgkin lymphoma. He received...
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