IMP-3 is differentially expressed in normal and neoplastic lymphoid tissue
Rebecca L. King, Theresa Pasha, Michele R. Roullet, Paul J. Zhang, Adam Bagg
20091101
2009 Dec 1
Hum Pathol
IMP-3 is differentially expressed in normal and neoplastic lymphoid tissue
Hum Pathol. 2009 Dec;40(12):1699-1705, Rebecca L. King, Theresa Pasha, Michele R. Roullet, Paul J. Zhang, Adam Bagg
IMP-3 is a member of the insulin-like growth factor II mRNA binding protein (IMP) family of proteins that play a role in RNA trafficking and stabilization and cell growth and migration during embryogenesis but which are down-regulated in adult tissue. However, IMP-3 has recently been shown to be overexpressed in several epithelial malignancies, with increased expression correlating with aggressive behavior. To our knowledge, there is no published literature evaluating IMP-3 in lymphoid tissue. Accordingly,...