Expression of Grb2 distinguishes classical Hodgkin lymphomas from primary mediastinal B-cell lymphomas and other diffuse large B-cell lymphomas
Rodney R. Miles, Cohra C. Mankey, Charlie E. Seiler, Lauren B. Smith, Julie Teruya-Feldstein, Eric D. Hsi, Kojo S.J. Elenitoba-Johnson, Megan S. Lim
20091101
2009 Dec 1
Hum Pathol
Expression of Grb2 distinguishes classical Hodgkin lymphomas from primary mediastinal B-cell lymphomas and other diffuse large B-cell lymphomas
Hum Pathol. 2009 Dec;40(12):1731-1737, Rodney R. Miles, Cohra C. Mankey, Charlie E. Seiler, Lauren B. Smith, Julie Teruya-Feldstein, Eric D. Hsi, Kojo S.J. Elenitoba-Johnson, Megan S. Lim
ABSTRACT
Growth factor receptor-bound protein 2 is an adaptor molecule that mediates B-cell receptor (BCR) signaling pathways, but the expression of growth factor receptor-bound protein 2 in lymphoma tissues has not been reported. We sought to characterize growth factor receptor-bound protein 2 protein expression in reactive tonsillar tissues and lymphoma tissues obtained from diagnostic biopsies of classical Hodgkin lymphoma, primary mediastinal large B-cell lymphoma, diffuse large B-cell lymphoma, nodular...
