Immunoprofile of mesenchymal chondrosarcoma: aberrant desmin and EMA expression, retention of INI1, and negative estrogen receptor in 22 female-predominant central nervous system and musculoskeletal cases
Julie C. Fanburg-Smith, Aaron Auerbach, Jayson S. Marwaha, Zengfeng Wang, Mariarita Santi, Alexander R. Judkins, Elisabeth J. Rushing
20100101
2010 Feb 1
Ann Diagn Pathol
Immunoprofile of mesenchymal chondrosarcoma: aberrant desmin and EMA expression, retention of INI1, and negative estrogen receptor in 22 female-predominant central nervous system and musculoskeletal cases
Ann Diagn Pathol. 2010 Feb;14(1):8-14, Julie C. Fanburg-Smith, Aaron Auerbach, Jayson S. Marwaha, Zengfeng Wang, Mariarita Santi, Alexander R. Judkins, Elisabeth J. Rushing
Mesenchymal chondrosarcoma is a rare malignant tumor in the differential diagnosis of other small, round blue cell tumors, including atypical teratoid tumor in the central nervous system (CNS) and rhabdomyosarcoma in the musculoskeletal (MSK) locations. We reviewed the morphology of CNS and MSK cases and applied a panel of immunostains. Archival cases were pulled from our files. Immunohistochemistry and follow-up were obtained. Twenty-two cases included 5 CNS (all female; mean age, 30.2) and 17 MSK...
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