Concurrent diagnoses of Hodgkin lymphoma and biclonal myeloma in the bone marrow
Alison R. Huppmann, Min-ling Liu, Victor E. Nava
20100701
2010 Aug 1
Ann Diagn Pathol
Concurrent diagnoses of Hodgkin lymphoma and biclonal myeloma in the bone marrow
Ann Diagn Pathol. 2010 Aug;14(4):268-272, Alison R. Huppmann, Min-ling Liu, Victor E. Nava
The diagnoses of Hodgkin lymphoma and multiple myeloma have rarely been made simultaneously in the same patient. We present a case of an 82-year-old man who rapidly developed pancytopenia and liver failure with coagulopathy. Serum protein electrophoresis and immunofixation revealed an unequivocal immunoglobulin Gκ and immunoglobulin Gλ biclonal gammopathy. Bone marrow biopsy showed involvement by classic Hodgkin lymphoma with an inflammatory background including 49% mature plasma cells. Unfortunately,...