Concurrent diagnoses of Hodgkin lymphoma and biclonal myeloma in the bone marrow

Ann Diagn Pathol. 2010 Aug;14(4):268-272, Alison R. Huppmann, Min-ling Liu, Victor E. Nava

The diagnoses of Hodgkin lymphoma and multiple myeloma have rarely been made simultaneously in the same patient. We present a case of an 82-year-old man who rapidly developed pancytopenia and liver failure with coagulopathy. Serum protein electrophoresis and immunofixation revealed an unequivocal immunoglobulin Gκ and immunoglobulin Gλ biclonal gammopathy. Bone marrow biopsy showed involvement by classic Hodgkin lymphoma with an inflammatory background including 49% mature plasma cells. Unfortunately,...

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