p16INK4A overexpression in precancerous and cancerous lesions of the uterine cervix in Tunisian women
Nabiha Missaoui, Amel Trabelsi, Sihem Hmissa, Bernard Fontanière, Mohamed Tahar Yacoubi, Moncef Mokni, Sadok Korbi, Lucien Frappart
20100701
2010 Aug 1
Pathol Res Pract
p16INK4A overexpression in precancerous and cancerous lesions of the uterine cervix in Tunisian women
Pathol Res Pract. 2010 Aug 15;206(8):550-555, Nabiha Missaoui, Amel Trabelsi, Sihem Hmissa, Bernard Fontanière, Mohamed Tahar Yacoubi, Moncef Mokni, Sadok Korbi, Lucien Frappart
Uterine cervix cancer is an important public health problem in developing countries. However, there is a substantial lack of inter-observer diagnostic reproducibility for its precursor lesions (CIN1). The study was performed to evaluate the usefulness of p16INK4A overexpression as a surrogate marker for uterine cervix precancerous lesions and high-risk human papillomavirus (HPV) infection.We conducted a retrospective study of 87 uterine cervix specimens, including 7 normal tissue samples, 17 benign...
Editors' Choice
Long-Term Posttransplant Bortezomib Boosts Outcome in Myeloma With del(17p13)
