Quantitative breath analysis of volatile organic compounds of lung cancer patients
Geng Song, Tao Qin, Hu Liu, Guo-Bing Xu, Yue-Yin Pan, Fu-Xing Xiong, Kang-Sheng Gu, Guo-Ping Sun, Zhen-Dong Chen
20100101
2010 Feb 1
Lung Cancer
Quantitative breath analysis of volatile organic compounds of lung cancer patients
Lung Cancer. 2010 Feb;67(2):227-231, Geng Song, Tao Qin, Hu Liu, Guo-Bing Xu, Yue-Yin Pan, Fu-Xing Xiong, Kang-Sheng Gu, Guo-Ping Sun, Zhen-Dong Chen
ABSTRACT
Due to state-of-art analytical techniques, non-invasive exhaled volatile organic compounds (VOCs) analysis has become a potential method for early diagnosis of lung cancer. We collected breath samples from 43 patients with non-small cell lung cancer (NSCLC) and 41 normal controls using Tedlar® gas bags. The VOCs were extracted with solid phase micro-extraction (SPME) and analyzed by gas chromatography (GC)/mass spectrometry (MS). The number of VOCs detected in each breath sample ranged from 68 to...