Expression of syncytin in leukemia and lymphoma cells

Leuk Res. 2010 Sept;34(9):1195-1202, Yi Sun, Dong-Yun Ouyang, Wei Pang, Yuan-Quan Tu, Yu-Ye Li, Xiao-Mei Shen, Siu-Cheung Tam, Hong-Ying Yang, Yong-Tang Zheng

Syncytin is a placenta-specific protein and generally believed to play a pivotal role in syncytiotrophoblast morphogenesis. In this study, transcripts of this gene were quantified by real-time RT-PCR and the translated products were measured by an indirect immunofluorescence assay. Results showed that syncytin was found to be expressed in all nine leukemia and lymphoma cell lines studied albeit at different levels and in 43 peripheral blood samples of 57 leukemia or lymphoma patients. Neither the...

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