Detection of circulating lymphoma cells in patients with non-Hodgkin lymphoma using MAGE-A3 gene expression in peripheral blood
Mi Hwa Han, Hyeon-Seok Eom, Weon-Seo Park, Tak Yun, Sohee Park, Hyun-Ju Kim, Chang-Ho Jeon, Sun-Young Kong
20100801
2010 Sept 1
Leuk Res
Detection of circulating lymphoma cells in patients with non-Hodgkin lymphoma using MAGE-A3 gene expression in peripheral blood
Leuk Res. 2010 Sept;34(9):1127-1131, Mi Hwa Han, Hyeon-Seok Eom, Weon-Seo Park, Tak Yun, Sohee Park, Hyun-Ju Kim, Chang-Ho Jeon, Sun-Young Kong
Background/AIMSLymphoma-specific gene expression in peripheral blood reflects the presence of circulating lymphoma cells (CLCs). MAGE-A3 is widely expressed in solid tumors and is a potent candidate for immunotherapy. To determine whether MAGE-A3 expression would be a useful marker for CLCs in non-Hodgkin lymphoma (NHL), we assessed MAGE-A3 mRNA expression in the peripheral blood of NHL patients and controls.MethodsWe measured MAGE-A3 gene expression in ten lymphoma cell lines (Farage, RL, SU-DHL,...
Editors' Choice
Long-Term Posttransplant Bortezomib Boosts Outcome in Myeloma With del(17p13)
