Torquetenovirus viremia kinetics after autologous stem cell transplantation are predictable and may serve as a surrogate marker of functional immune reconstitution
Daniele Focosi, Fabrizio Maggi, Melania Albani, Lisa Macera, Valentina Ricci, Silvia Gragnani, Serena Di Beo, Massimo Ghimenti, Guido Antonelli, Mauro Bendinelli, Mauro Pistello, Luca Ceccherini-Nelli, Mario Petrini
20100101
2010 Feb 1
J Clin Virol
Torquetenovirus viremia kinetics after autologous stem cell transplantation are predictable and may serve as a surrogate marker of functional immune reconstitution
J Clin Virol. 2010 Feb;47(2):189-192, Daniele Focosi, Fabrizio Maggi, Melania Albani, Lisa Macera, Valentina Ricci, Silvia Gragnani, Serena Di Beo, Massimo Ghimenti, Guido Antonelli, Mauro Bendinelli, Mauro Pistello, Luca Ceccherini-Nelli, Mario Petrini
ABSTRACT
BackgroundIt is common experience that retreating patients too early after a course of intensive chemotherapy predisposes to opportunistic infections despite apparently normal lymphocyte levels.ObjectivesThe extent of replication of persistent viruses that cause no obvious disease (and hence need no treatment) might better define when a patient has recovered from functional immune deficiency.Study designWe used real-time polymerase chain reaction to monitor the kinetics of plasma torquetenovirus...
