Relevance of HPV mRNA detection in a population of ASCUS plus women using the NucliSENS EasyQ® HPV assay
Philippe Halfon, Dominique Benmoura, Aubert Agostini, Hacene Khiri, Agnés Martineau, Guillaume Penaranda, Bernard Blanc
20100101
2010 Feb 1
J Clin Virol
Relevance of HPV mRNA detection in a population of ASCUS plus women using the NucliSENS EasyQ® HPV assay
J Clin Virol. 2010 Feb;47(2):177-181, Philippe Halfon, Dominique Benmoura, Aubert Agostini, Hacene Khiri, Agnés Martineau, Guillaume Penaranda, Bernard Blanc
BackgroundDNA- and mRNA-based assays are the main tools used for detecting human papillomavirus (HPV) nucleic acid in clinical samples. A recent tool, NucliSENS EasyQ HPV, uses a new concept to directly detect the expression of HPV oncogenic factors (E6 and E7) from the most prevalent HPV genotypes in cervical cancer (16, 18, 31, 33 and 45).ObjectivesThe primary aim of the study is to assess the accuracy of NucliSENS EasyQ HPV in detecting high-risk (HR) HPV in a population of atypical cells of undetermined...
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