A comparison of ad hoc methods to account for non-cancer AIDS and deaths as competing risks when estimating the effect of HAART on incident cancer AIDS among HIV-infected men
Meredith S. Shiels, Stephen R. Cole, Joan S. Chmiel, Joseph Margolick, Jeremy Martinson, Zuo-Feng Zhang, Lisa P. Jacobson
20100301
2010 Apr 1
J Clin Epidemiol
A comparison of ad hoc methods to account for non-cancer AIDS and deaths as competing risks when estimating the effect of HAART on incident cancer AIDS among HIV-infected men
J Clin Epidemiol. 2010 Apr;63(4):459-467, Meredith S. Shiels, Stephen R. Cole, Joan S. Chmiel, Joseph Margolick, Jeremy Martinson, Zuo-Feng Zhang, Lisa P. Jacobson
ObjectiveTo compare three ad hoc methods to estimate the marginal hazard of incident cancer acquired immune deficiency syndrome (AIDS) in a highly active antiretroviral therapy (1996–2006) relative to a monotherapy/combination therapy (1990–1996) calendar period, accounting for other AIDS events and deaths as competing risks.Study Design and SettingAmong 1,911 human immunodeficiency virus (HIV)-positive men from the Multicenter AIDS Cohort Study, 228 developed cancer AIDS and 745 developed competing...