ider(17)(q10)t(15;17) associated with relapse and poor prognosis in a pediatric patient with acute promyelocytic leukemia
Min Jin Kim, Hoi Soo Yoon, Sun Young Cho, Hee Joo Lee, Jin-Tae Suh, Juhie Lee, Hwi-Joong Yoon, Woo-In Lee, Tae Sung Park
20100801
2010 Sept 1
Cancer Genet Cytogenet
ider(17)(q10)t(15;17) associated with relapse and poor prognosis in a pediatric patient with acute promyelocytic leukemia
Cancer Genet Cytogenet. 2010 Sept;201(2):116-121, Min Jin Kim, Hoi Soo Yoon, Sun Young Cho, Hee Joo Lee, Jin-Tae Suh, Juhie Lee, Hwi-Joong Yoon, Woo-In Lee, Tae Sung Park
Although acute promyelocytic leukemia (APL) has been regarded as a serious medical emergency associated with disseminated intravascular coagulopathy or subsequent mortality, it is now considered a curable leukemia that is particularly sensitive to treatment with all-trans retinoic acid combined with chemotherapy. However, it is not clear whether additional chromosomal abnormalities in APL patients directly influence the prognosis or treatment response. ider(17)(q10)t(15;17)(q22;q21) has mostly been...