Newly described translocation (18;19)(q23;q13.2) in abdominal wall soft-tissue tumor resembling Ewing sarcoma/primitive neuroectodermal tumor
Gina F. Riccardi, Constance Stein, Gustavo de la Roza, Timothy A. Damron
20100701
2010 Aug 1
Cancer Genet Cytogenet
Newly described translocation (18;19)(q23;q13.2) in abdominal wall soft-tissue tumor resembling Ewing sarcoma/primitive neuroectodermal tumor
Cancer Genet Cytogenet. 2010 Aug;201(1):1-5, Gina F. Riccardi, Constance Stein, Gustavo de la Roza, Timothy A. Damron
From a morphologic standpoint, Ewing sarcoma (EWS) is one of a number of pediatric malignancies that are characterized by sheets of small, round, blue cells. Ewing sarcoma can usually be differentiated from other small round blue cell tumors by the presence of a gene rearrangement having a consistent breakpoint within the Ewing sarcoma gene (EWSR1) at 22q12. Although the most common translocation partner is FLI1, located at 11q24, there is a growing list of alternate rearrangements involving different...
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