Raloxifene and Risk for Stroke Based on the Framingham Stroke Risk Score
Elizabeth Barrett-Connor, David A. Cox, Jingli Song, Bruce Mitlak, Lori Mosca, Deborah Grady
20090701
2009 Aug 1
Am J Med
Yes
Raloxifene and Risk for Stroke Based on the Framingham Stroke Risk Score
Am J Med. 2009 Aug;122(8):754-761, Elizabeth Barrett-Connor, David A. Cox, Jingli Song, Bruce Mitlak, Lori Mosca, Deborah Grady
Purpose Raloxifene reduces vertebral fracture and invasive breast cancer risks, but increases fatal strokes in postmenopausal women at increased coronary risk. We assessed whether this risk is concentrated in postmenopausal women already at high stroke risk. Methods Raloxifene Use for The Heart (RUTH) enrolled 10,101 postmenopausal women (mean age 67 years) with or at increased coronary heart disease risk; Multiple Outcomes of Raloxifene Evaluation (MORE) enrolled 7705 osteoporotic postmenopausal...
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