Risk of Classic Kaposi Sarcoma with Residential Exposure to Volcanic and Related Soils in Sicily

Ann Epidemiol. 2009 Aug;19(8):597-601, Colleen Pelser, Carmelo Dazzi, Barry I. Graubard, Carmela Lauria, Francesco Vitale, James J. Goedert

PurposeBefore AIDS, endemic (African) Kaposi sarcoma (KS) was noted to occur in volcanic areas and was postulated to result from dirt chronically embedded in the skin of the lower extremities. The primary cause of all KS types is KS-associated herpesvirus (KSHV) infection, but cofactors contribute to the neoplasia. We investigated whether residential exposure to volcanic or related soils was associated with the risk of classic Kaposi sarcoma (cKS) in Sicily.MethodsRisk of incident cKS (N=141) compared...

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