KRAS Mutation Status Predicts Response to Panitumumab in Patients With Advanced Colorectal Cancer

2008 Jan 24, ASCO 2008 Gastrointestinal Cancer Symposium Press Kit

In the first randomized trial of KRAS  (pronounced K-Rass) status and response to the targeted therapy panitumumab (Vectibix), researchers have confirmed that patients with advanced colorectal cancer benefit from the drug only if they have a normal form of the gene KRAS  present in their tumors, rather than a mutated KRAS  gene. KRAS  mutations are found in 30 to 50 percent of colorectal cancer patients. These are the latest findings in the field of "personalized medicine," which evaluate the potential...

NOT A MEMBER?

Registration is FREE

  • Up-to-date oncology news
  • Journal article summaries
  • Commentaries and interviews
  • Drug and interactions database
  • Chemotherapy regimens
  • Daily e-newsletters

 

Editors' Choice

Long-Term Posttransplant Bortezomib Boosts Outcome in Myeloma With del(17p13)

Cancer Type

  • Bladder
  • Bone
  • Breast
  • Breast (ER-Positive)
  • CNS/Brain
  • Colon and Rectum
  • Endocrine System
  • Esophagus
  • GYN (Non-Ovary)
  • GYN (Ovary)
  • Head and Neck
  • Hodgkin's Lymphoma
  • Kidney (Renal Cell)
  • Leukemia
  • Liver and Bile Duct
  • Lung
  • Multiple Myeloma
  • Myelodysplastic Syndrome
  • Myeloproliferative Diseases
  • Non-Hodgkin's Lymphoma
  • Pancreas
  • Pediatric Cancers
  • Prostate
  • Rare Cancers
  • Skin
  • Soft-Tissue Sarcoma
  • Stomach
  • Testicle
  • Forgot your password?
    Not a member? Free registration